IL-6 anticorps

N° du produit ABIN1383946

Cet anticorps Souris Monoclonal détecte spécifiquement IL-6 dans WB, IHC et FACS. Il présente une réactivité envers Humain et Souris et a été mentionné dans 5+ publications.

Aperçu rapide pour IL-6 anticorps (ABIN1383946)

Antigène: IL-6 (IL6) (Interleukin 6 (IL6))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: B-F6

Détail du produit anti-IL-6 anticorps

Specificité: Recognises both natural and recombinant human IL-6

Purification: Ion exchange chromatography

Stérilité: 0.22 μm filtered

Immunogène: Recombinant human IL-6,Myeloma X63/AG.8653 x Balb/c spleen cells

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

Agent conservateur: Without preservative

Stock: 4 °C

Stockage commentaire: Stable at +2-8°C for 12 months. For longer storage freeze aliquots.

Références pour anticorps anti-IL-6 (ABIN1383946)

Kube, Holtick, Vockerodt, Ahmadi, Haier, Behrmann, Heinrich, Diehl, Tesch: "STAT3 is constitutively activated in Hodgkin cell lines." dans: Blood, Vol. 98, Issue 3, pp. 762-70, (2001) (PubMed).

Voorzanger, Touitou, Garcia, Delecluse, Rousset, Joab, Favrot, Blay: "Interleukin (IL)-10 and IL-6 are produced in vivo by non-Hodgkin's lymphoma cells and act as cooperative growth factors." dans: Cancer research, Vol. 56, Issue 23, pp. 5499-505, (1997) (PubMed).

Wijdenes, Heinrich, Müller-Newen, Roche, Gu, Clément, Klein: "Interleukin-6 signal transducer gp130 has specific binding sites for different cytokines as determined by antagonistic and agonistic anti-gp130 monoclonal antibodies." dans: European journal of immunology, Vol. 25, Issue 12, pp. 3474-81, (1996) (PubMed).

Zunino, Singh, Bass, Picker: "Immunodetection of histone epitopes correlates with early stages of apoptosis in activated human peripheral T lymphocytes." dans: The American journal of pathology, Vol. 149, Issue 2, pp. 653-63, (1996) (PubMed).

Wijdenes, Clement, Klein, Morel-Fourrier, Vita, Ferrara, Peters: "Human recombinant dimeric IL-6 binds to its receptor as detected by anti-IL-6 monoclonal antibodies." dans: Molecular immunology, Vol. 28, Issue 11, pp. 1183-92, (1992) (PubMed).

Détails sur IL-6

Antigène: IL-6 (IL6) (Interleukin 6 (IL6))

Autre désignation: IL-6

Pathways: Signalisation TLR, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome